A 73-year-old woman visited our hospital with a complaint of epigastric pain, and a small elevated lesion was pointed out in the anterior wall of the angular part of the stomach. Immunohistochemical staining of a biopsy specimen proved that the lesion was plasmacytoma. EUS examination revealed invasion of the tumor cells to submucosal layer. Serum M protein or Bence Jones protein was not identified. Myelogram and Ga scintigram showed no abnormal findings, indicating a diagnosis of extramedullary plasmacytoma of the stomach. Subtotal gastrectomy was performed on August 2, 1991. In the resected specimen, the elevated lesion was 14 X 11mm in size, and tumor cells invaded into sub-mucosal layer, compatible with the EUS finding.
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