TY - JOUR
T1 - A case of invasive fungal sphenoiditis treated by sphenoid drill-out
AU - Makihara, Seiichiro
AU - Okano, Mitsuhiro
AU - Ishihara, Hisashi
AU - Miyatake, Tomomi
AU - Tsumura, Munechika
AU - Kariya, Shin
AU - Nishizaki, Kazunori
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 2014/8
Y1 - 2014/8
N2 - We present a 68-year-old man suffered from invasive fungal sphenoiditis. The patient complained of right eye pain and headache. His sphenoiditis was refractory to both medical management of VRCZ and sphenoidotomy, and finally he underwent sphenoid drill-out. After the final surgery, we performed therapeutic drug monitoring (TDM) and managed the internal use of VRCZ thoroughly. After a year, he has been doing well. When the clinical response is poor, or side effects are developed, measurement of the TDM is important as a tool of medical management.
AB - We present a 68-year-old man suffered from invasive fungal sphenoiditis. The patient complained of right eye pain and headache. His sphenoiditis was refractory to both medical management of VRCZ and sphenoidotomy, and finally he underwent sphenoid drill-out. After the final surgery, we performed therapeutic drug monitoring (TDM) and managed the internal use of VRCZ thoroughly. After a year, he has been doing well. When the clinical response is poor, or side effects are developed, measurement of the TDM is important as a tool of medical management.
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M3 - Article
AN - SCOPUS:84906873820
SN - 0914-3491
VL - 86
SP - 765
EP - 770
JO - Otolaryngology - Head and Neck Surgery (Tokyo)
JF - Otolaryngology - Head and Neck Surgery (Tokyo)
IS - 9
ER -