TY - JOUR
T1 - A Case of Lung Cancer That Showed an Abscopal Effect after Irradiation of Simultaneous Oropharyngeal Cancer
AU - Nakamura, Kayo
AU - Ichihara, Eiki
AU - Shibata, Yusaku
AU - Murakami, Etsuko
AU - Miyahara, Nobuaki
AU - Kishino, Daizo
N1 - Publisher Copyright:
© 2021 Japan Lung Cancer Society. All rights reserved.
PY - 2021
Y1 - 2021
N2 - Background. The abscopal effect is a phenomenon in which tumor shrinkage occurs outside the radiation field. It usually occurs between the primary tumor and metastatic lesions of the same cancer or between metastatic lesions, and there have been no reports on the abscopal effect occurring after irradiation of other cancer types. Case. A woman in her 50s was diagnosed with double primary cancer of lung and oropharyngeal cancer. After the administration of nivolumab as second-line treatment for lung cancer, the lung cancer did not show any increase in size for six months (stable disease). However, the pharyngeal cancer showed progression, so irradiation was started for it. After radiotherapy, shrinkage of the primary lung cancer (outside the irradiation field) was observed. Conclusion. We experienced a case in which primary lung cancer shrank after irradiation for primary pharyngeal cancer. This case suggests that abscopal-like effects may occur between different cancer types.
AB - Background. The abscopal effect is a phenomenon in which tumor shrinkage occurs outside the radiation field. It usually occurs between the primary tumor and metastatic lesions of the same cancer or between metastatic lesions, and there have been no reports on the abscopal effect occurring after irradiation of other cancer types. Case. A woman in her 50s was diagnosed with double primary cancer of lung and oropharyngeal cancer. After the administration of nivolumab as second-line treatment for lung cancer, the lung cancer did not show any increase in size for six months (stable disease). However, the pharyngeal cancer showed progression, so irradiation was started for it. After radiotherapy, shrinkage of the primary lung cancer (outside the irradiation field) was observed. Conclusion. We experienced a case in which primary lung cancer shrank after irradiation for primary pharyngeal cancer. This case suggests that abscopal-like effects may occur between different cancer types.
KW - Abscopal effect
KW - Immune checkpoint inhibitor
KW - Non-small cell lung cancer
KW - Pharyngeal cancer. radiation therapy
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U2 - 10.2482/HAIGAN.61.109
DO - 10.2482/HAIGAN.61.109
M3 - Article
AN - SCOPUS:85106388912
SN - 0386-9628
VL - 91
SP - 109
EP - 112
JO - Japanese Journal of Lung Cancer
JF - Japanese Journal of Lung Cancer
IS - 2
ER -