TY - JOUR
T1 - A unique case with positive anti-myelin oligodendrocyte glycoprotein antibody presenting multiple brain lesions
AU - Matsumoto, Namiko
AU - Sato, Kota
AU - Hishikawa, Nozomi
AU - Kawahara, Yuko
AU - Takemoto, Mami
AU - Ohta, Yasuyuki
AU - Yamashita, Toru
AU - Fujii, Kentaro
AU - Kurozumi, Kazuhiko
AU - Date, Isao
AU - Takahashi, Toshiyuki
AU - Abe, Koji
N1 - Publisher Copyright:
© 2019 Japanese Society of Neurology and John Wiley & Sons Australia, Ltd
PY - 2020/3/1
Y1 - 2020/3/1
N2 - The accurate diagnosis of anti-myelin oligodendrocyte glycoprotein (MOG) antibody-associated diseases is sometimes challenging due to its various central nervous system (CNS) lesions. Here, we report a 22-year-old man with positive anti-MOG antibody presenting multiple brain lesions including a brainstem tumefactive demyelinating lesion (TDL), cortical edematous lesions, and a periventricular white matter lesion. These variety of lesions made the diagnosis challenging, especially because TDL is quite rare among MOG antibody-associated disease patients. The present case suggests the importance to check anti-MOG antibody for patients presenting atypical multiple CNS lesions.
AB - The accurate diagnosis of anti-myelin oligodendrocyte glycoprotein (MOG) antibody-associated diseases is sometimes challenging due to its various central nervous system (CNS) lesions. Here, we report a 22-year-old man with positive anti-MOG antibody presenting multiple brain lesions including a brainstem tumefactive demyelinating lesion (TDL), cortical edematous lesions, and a periventricular white matter lesion. These variety of lesions made the diagnosis challenging, especially because TDL is quite rare among MOG antibody-associated disease patients. The present case suggests the importance to check anti-MOG antibody for patients presenting atypical multiple CNS lesions.
KW - clinically isolated syndrome
KW - MS and related diseases
KW - myelin oligodendrocyte glycoprotein
KW - neuromyelitis optica spectrum disorder
KW - tumefactive demyelinating lesion
UR - https://www.scopus.com/pages/publications/85098650492
UR - https://www.scopus.com/pages/publications/85098650492#tab=citedBy
U2 - 10.1111/ncn3.12364
DO - 10.1111/ncn3.12364
M3 - Article
AN - SCOPUS:85098650492
SN - 2049-4173
VL - 8
SP - 92
EP - 95
JO - Neurology and Clinical Neuroscience
JF - Neurology and Clinical Neuroscience
IS - 2
ER -