Asymmetric reduction of ethyl 2-methyl 3-oxobutanoate by chlorella

Takayuki Kuramoto, Kenzo Iwamoto, Minoru Izumi, Mitsunori Kirihata, Fumiki Yoshizako

研究成果査読

13 被引用数 (Scopus)

抄録

Chlorella pyrenoidosa Chick reduced ethyl 2-methyl 3-oxobutanoate to the corresponding alcohols with the diastereomer (anti/syn) ratio of 53/47. The enantiomer excesses of anti-(2S, 3S)- and syn-(2S, 3R)-hydroxy esters were 89 and >99ee% respectively. C. vulgaris and C. regularis afforded predominantly the syn-isomer, contrary to C. pyrenoidosa. The differences in the activity of reducing ethyl 2-methyl 3-oxobutanoate were observed among three strains of Chlorella. Addition of 2% metal salts slightly increased the chemical yield of the hydroxy ester.

本文言語English
ページ(範囲)598-601
ページ数4
ジャーナルBioscience, Biotechnology and Biochemistry
63
3
DOI
出版ステータスPublished - 1月 1 1999
外部発表はい

ASJC Scopus subject areas

  • バイオテクノロジー
  • 分析化学
  • 生化学
  • 応用微生物学とバイオテクノロジー
  • 分子生物学
  • 有機化学

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