Dilute Hydrofluoric Acid as a Fluorinating Agent: Iodofluorination of Olefins with Dilute Hydrofluoric Acid, N -Iodosuccinimide, and a Phase Transfer Catalyst

Manabu Kuroboshi; Tamejiro Hiyama

doi:10.1055/s-1991-20672

Dilute Hydrofluoric Acid as a Fluorinating Agent: Iodofluorination of Olefins with Dilute Hydrofluoric Acid, N -Iodosuccinimide, and a Phase Transfer Catalyst

Manabu Kuroboshi
, Tamejiro Hiyama

研究成果 › 査読

9 被引用数 (Scopus)

抄録

Regio-, stereo-, and chemoselective iodofluorination of olefins is readily effected under a two-phase system using dilute hydrofluoric acid, N-iodosuccinimide, and tetrabutylammonium fluoride as a phase transfer catalyst. Additional use of potassium hydrogen fluoride (KHF ₂ ) enhanced the yields of fluoro-iodo adducts and suppressed the formation of iodohydrins as byproducts.

本文言語	English
ページ（範囲）	185-186
ページ数	2
ジャーナル	Synlett
巻	1991
号	3
DOI	https://doi.org/10.1055/s-1991-20672
出版ステータス	Published - 3月 1991
外部発表	はい

ASJC Scopus subject areas

有機化学

文献へのアクセス

10.1055/s-1991-20672

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引用スタイル

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