Double high-dose chemotherapy supported by autologous transplantation of peripheral blood stem cells for treatment of an elderly patient with small-cell lung cancer

Hiromichi Yamane, Akihiro Bessho, Katsuyuki Kiura, Masahiro Tabata, Yoshio Katayama, Kinya Motoda, Tadashi Tsuchida, Naoyuki Nogami, Akio Hiraki, Hiroshi Ueoka, Mine Harada

研究成果査読

1 被引用数 (Scopus)

抄録

We report a 62-year-old male with extensive disease small-cell lung cancer (SCLC) who was successfully treated with double high-dose chemotherapy supported by autologous peripheral blood stem cell transplantation (auto-PBSCT). This patient achieved a partial response with 3 cycles of induction chemotherapy. After the peripheral blood stem cell mobilization, two cycles of high-dose ICE regimen (ifosfamide 3,000 mg/m2 at days 1 to 5, carboplatin 400 mg/m2 at days 1,3, 5, and etoposide 500 mg/m2 at days 1,3,5) could be given with further regression of the tumor and acceptable toxicities. This successful case suggests the feasibility of double high-dose ICE with auto-PBSCT in elderly patients with SCLC.

本文言語English
ページ(範囲)892-895
ページ数4
ジャーナルInternal Medicine
38
11
DOI
出版ステータスPublished - 11月 1999

ASJC Scopus subject areas

  • 内科学

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