抄録
Redox regulation has recently been recognized as an important factor in acute illnesses as well as in chronic diseases. It has also become a target for neuroprotection in acute intensive care. Despite its well-known therapeutic effects, therapeutic hypothermia has recently been re-evaluated for its potential use in emergency and critical care medicine. Hypothermia is an undesirable physiological condition that can increase oxidative stress and decrease anti-oxidative potency. However, many studies have shown that under ischemia/reperfusion conditions, therapeutic hypothermia actually suppresses enhanced oxidative stress and maintains or increases anti-oxidative potency. This review provides an overview and outlook for the future of therapeutic hypothermia for neuroprotection from the perspective of redox regulation in patients with post-cardiac arrest syndrome and traumatic brain injury.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 1-9 |
| ページ数 | 9 |
| ジャーナル | Acta medica Okayama |
| 巻 | 71 |
| 号 | 1 |
| 出版ステータス | Published - 2017 |
ASJC Scopus subject areas
- 生化学、遺伝学、分子生物学（全般）