In this immunohistochemical examination, the expression of Notch1 peptide was detected in neo-plastic cells in a case of osteosarcoma of the maxilla of a 31 -year-old Indonesian male patient. Notch1 peptide appeared in the cytoplasm of neoplastic cells of comparatively well-differentiated areas of the osteosarcoma, an osteoblastic area containing osteoid and/or immature bone tissues. The results suggest that Notch1 is closely related to cytological differentiation of acquisition of cytological characteristics in neoplastic cells of osteosarcoma.
|ジャーナル||European journal of medical research|
|出版ステータス||Published - 2004|
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