Fibrillar ultrastructure of the glomerular basement membrane of the rat kidney as revealed by digestive treatment.

A. Ichiyasu, M. Takaoka, H. Makino, K. Takahashi, Z. Ota

研究成果査読

抄録

Rat kidney glomerular basement membrane (GBM) was isolated and digested with alpha-amylase and elastase. Electron microscopy revealed a meshwork structure composed of fibrils 3 nm in width. They appeared to be type IV collagen fibrils. We succeeded in clarifying a significant ultrastructural aspect of the GBM which had been unclear until now. The findings are consistent with our previously proposed GBM molecular sieve theory.

本文言語English
ページ(範囲)183-185
ページ数3
ジャーナルActa medica Okayama
41
4
出版ステータスPublished - 8月 1987

ASJC Scopus subject areas

  • 生化学、遺伝学、分子生物学一般

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