Highly efficient production of l-cystathionine from O-succinyl-l-homoserine and l-cysteine by Streptomyces cystathionine γ-lyase

Hiroshi Kanzaki, Toru Nagasawa, Hideaki Yamada

研究成果査読

5 被引用数 (Scopus)

抄録

Utilizing the γ-replacement reaction of Streptomyces cystathionine γ-lyase (EC 4.4.1.1.), an efficient production method for l-cystathionine has been established. Under optimal conditions, 50 mM l-cystathionine was synthesized from 50 mM O-succinyl-l-homoserine and 50 mM l-cysteine, added in four stages to the reaction mixture, with a substrate conversion rate of 100%. This productivity (11 gl-1 of reaction mixture) is about 3.5 times higher than that with l-homoserine and l-cysteine as substrates.

本文言語English
ページ(範囲)97-100
ページ数4
ジャーナルApplied Microbiology and Biotechnology
25
2
DOI
出版ステータスPublished - 11月 1986
外部発表はい

ASJC Scopus subject areas

  • バイオテクノロジー
  • 応用微生物学とバイオテクノロジー

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