TY - CONF
T1 - Improvement of cell adhesiveness of poly(ethylene terephthalate) by surface modification with hydroxyapatite nanocrystals through covalent bonding
AU - Masuda, Miwa
AU - Yasuda, Shoji
AU - Okada, Masahiro
AU - Tanaka, Ryoichi
AU - Miyatake, Kunio
AU - Furuzono, Tsutomu
PY - 2005/12/1
Y1 - 2005/12/1
N2 - In this study, a novel composite for a soft-tissue-compatible material was developed. A surface of poly(ethylene terephthalate) (PET) fabric was modified with nano-sized hydroxyapatite (HAp) crystals through covalent bonding. In order to make covalent bonding between the HAp crystal and the PET surface, poly(γ-methacryloxypropyl triethoxysilane) poly(MPTS) was grafted on the PET surface treated by H2O2. The surface modification of PET with poly(MPTS) was confirmed by the weight gaining and X-ray photoelectron spectroscopy. The chemical reaction between OH groups on the HAp crystals and ethoxysilyl groups on the PET was conducted at 80°C for 2h in reduced pressure. It was confirmed that HAp/PET composite was not toxic by microscopic observation. The cell adhesion test of HAp/PET composite will be reported on the presentation.
AB - In this study, a novel composite for a soft-tissue-compatible material was developed. A surface of poly(ethylene terephthalate) (PET) fabric was modified with nano-sized hydroxyapatite (HAp) crystals through covalent bonding. In order to make covalent bonding between the HAp crystal and the PET surface, poly(γ-methacryloxypropyl triethoxysilane) poly(MPTS) was grafted on the PET surface treated by H2O2. The surface modification of PET with poly(MPTS) was confirmed by the weight gaining and X-ray photoelectron spectroscopy. The chemical reaction between OH groups on the HAp crystals and ethoxysilyl groups on the PET was conducted at 80°C for 2h in reduced pressure. It was confirmed that HAp/PET composite was not toxic by microscopic observation. The cell adhesion test of HAp/PET composite will be reported on the presentation.
KW - Composite
KW - Endothelial cells
KW - HO
KW - Poly(ethylene terephthalate)
KW - Sintered hydroxyapatite
UR - http://www.scopus.com/inward/record.url?scp=33645641635&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33645641635&partnerID=8YFLogxK
M3 - Paper
AN - SCOPUS:33645641635
T2 - 54th SPSJ Annual Meeting 2005
Y2 - 25 May 2005 through 27 May 2005
ER -