Inhibitory effect of water-soluble chitosan on growth of Streptococcus mutans

M. Fujiwara, Y. Hayashi, N. Ohara

研究成果査読

29 被引用数 (Scopus)

抄録

The present study was undertaken to evaluate the effects of pH and the degree of polymerization of chitosan on the inhibition of growth of Streptococcus mutans. Three types of chitosan, polymer, oligomer and monomer, were used at 4%(W/V) and three different levels of pH: 6.0, 6.5 and 7.4. Bactericidal activity was calculated by the growth ratio. Chitosan oligomer significantly inhibited bacterial growth at a pH value of 6.5. All three types of chitosan strongly inhibited bacterial growth at pH 6.0. Furthermore, nearly complete inhibition was obtained with 2%(W/V) chitosan solution at constant pH 6.5. This study is the first to report that water-soluble chitosan directly suppresses the growth of the typical cariogenic bacterium S. mutans even at pH 6.5, without causing demoralization of the tooth surface.

本文言語English
ページ(範囲)83-86
ページ数4
ジャーナルNew Microbiologica
27
1
出版ステータスPublished - 1月 2004
外部発表はい

ASJC Scopus subject areas

  • 微生物学(医療)

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