Investigation of multilayered protein adsorption on carbonate apatite with a QCM technique

Tomohiko Yoshioka, Hiroshi Yonekura, Toshiyuki Ikoma, Motohiro Tagaya, Junzo Tanaka

研究成果

2 被引用数 (Scopus)

抄録

This study is concerned with multilayered protein adsorption on carbonate apatite (CAp) that is measured with a quartz crystal microbalance (QCM) technique. A carbonate apatite-deposited QCM sensor was prepared by electrophoretic deposition (EPD). On the CAp-deposited QCM sensor, fibrinogen adsorption followed by thrombin adsorption was investigated. The adsorption of fibrinogen on CAp led to a clear decrease in the resonance frequency of the sensor, which means that fibrinogen adsorbed on the CAp-deposited QCM sensor. The adsorbed amount of fibrinogen was larger on CAp than on a pristine sensor (Au). Although successive thrombin adsorption occurred on fibrinogen adlayers on both CAp and Au, the adsorbed amount and its conformation were different depending on the surface.

本文言語English
ホスト出版物のタイトルBioceramics 24
出版社Trans Tech Publications Ltd
ページ74-77
ページ数4
1
ISBN(印刷版)9783037855171
DOI
出版ステータスPublished - 2013
外部発表はい
イベント24th Symposium and Annual Meeting of International Society for Ceramics in Medicine, ISCM 2012 - Fukuoka
継続期間: 10月 21 201210月 24 2012

出版物シリーズ

名前Key Engineering Materials
番号1
529-530
ISSN(印刷版)1013-9826
ISSN(電子版)1662-9795

Other

Other24th Symposium and Annual Meeting of International Society for Ceramics in Medicine, ISCM 2012
国/地域Japan
CityFukuoka
Period10/21/1210/24/12

ASJC Scopus subject areas

  • 材料科学(全般)
  • 材料力学
  • 機械工学

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