@article{1f84e481ee5c4ddeb72a82978661b6a3,
title = "Kinetic Resolution of α-Nitrolactones by Catalytic Asymmetric Hydrolysis or Ester-Amide Exchange Reaction",
abstract = "C1 -Symmetric chiral ammonium salt catalysts induced a kinetic resolution of racemic α-nitrolactones through an asymmetric ester-amide exchange reaction. The corresponding amides were obtained with high enantioselectivities and high S (= k fast / k slow) values. This reaction system is a useful approach for obtaining carbocyclic quaternary α-nitroamides as chiral building blocks. ",
keywords = "Bronsted acid catalysis, ester-amide exchange, hydrolysis, kinetic resolution, nitrolactones, quaternary amino acids",
author = "Ryota Nakao and Yudai Fujii and Ichiro Hayakawa and Haruki Mizoguchi and Akira Sakakura",
note = "Funding Information: This work was supported in part by a Grant-in-Aid for Scientific Research (C) (No. 15K05123) from MEXT, the Naito Foundation, and the Okayama Foundation for Science and Technology.OkayamaFoundaionforScienceandTechnology(NaitoFoundatonMinitsyofEducaion, Culute, Spos, ScienceandTechnology(15K05123) Publisher Copyright: {\textcopyright} 2020. Thieme. All rights reserved.",
year = "2020",
month = dec,
day = "17",
doi = "10.1055/s-0040-1707303",
language = "English",
volume = "31",
pages = "2018--2022",
journal = "Synlett",
issn = "0936-5214",
publisher = "Georg Thieme Verlag",
number = "20",
}