Large ulceration of the oropharynx induced by methotrexate-associated lymphoproliferative disorders

Hiroyuki Hanakawa; Yorihisa Orita; Yasuharu Sato; Kinya Uno; Kazunori Nishizaki; Tadashi Yoshino

Large ulceration of the oropharynx induced by methotrexate-associated lymphoproliferative disorders

Hiroyuki Hanakawa, Yorihisa Orita, Yasuharu Sato, Kinya Uno, Kazunori Nishizaki, Tadashi Yoshino

研究成果 › 査読

抄録

We present a case of a 67-year-old Japanese man with a serious oropharyngeal ulceration that at first seemed to be destructive malignant lymphoma or oropharyngeal carcinoma. We suspected methotrexate (MTX)-associated lymphoproliferative disorder (LPD) induced by MTX treatment for rheumatoid arthritis (RA). About 3 weeks after simple discontinuation of MTX, complete regression of the disease was observed, confirming our diagnosis.

本文言語	English
ページ（範囲）	265-269
ページ数	5
ジャーナル	Acta medica Okayama
巻	67
号	4
出版ステータス	Published - 2013

ASJC Scopus subject areas

生化学、遺伝学、分子生物学（全般）

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abstract = "We present a case of a 67-year-old Japanese man with a serious oropharyngeal ulceration that at first seemed to be destructive malignant lymphoma or oropharyngeal carcinoma. We suspected methotrexate (MTX)-associated lymphoproliferative disorder (LPD) induced by MTX treatment for rheumatoid arthritis (RA). About 3 weeks after simple discontinuation of MTX, complete regression of the disease was observed, confirming our diagnosis.",

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T1 - Large ulceration of the oropharynx induced by methotrexate-associated lymphoproliferative disorders

AU - Hanakawa, Hiroyuki

AU - Orita, Yorihisa

AU - Sato, Yasuharu

AU - Uno, Kinya

AU - Nishizaki, Kazunori

AU - Yoshino, Tadashi

PY - 2013

Y1 - 2013

N2 - We present a case of a 67-year-old Japanese man with a serious oropharyngeal ulceration that at first seemed to be destructive malignant lymphoma or oropharyngeal carcinoma. We suspected methotrexate (MTX)-associated lymphoproliferative disorder (LPD) induced by MTX treatment for rheumatoid arthritis (RA). About 3 weeks after simple discontinuation of MTX, complete regression of the disease was observed, confirming our diagnosis.

AB - We present a case of a 67-year-old Japanese man with a serious oropharyngeal ulceration that at first seemed to be destructive malignant lymphoma or oropharyngeal carcinoma. We suspected methotrexate (MTX)-associated lymphoproliferative disorder (LPD) induced by MTX treatment for rheumatoid arthritis (RA). About 3 weeks after simple discontinuation of MTX, complete regression of the disease was observed, confirming our diagnosis.

KW - Lymphoproliferative disorders

KW - Methotrexate

KW - Oropharynx

KW - Ulceration

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JO - Acta Medica Okayama

JF - Acta Medica Okayama

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ER -

Large ulceration of the oropharynx induced by methotrexate-associated lymphoproliferative disorders

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