TY - GEN
T1 - Measurement of motor unit action potential in ischemic muscle using intramuscular probe
AU - Oka, Hisao
AU - Isshiki, Hiromi
AU - Öberg, P. Åke
N1 - Publisher Copyright:
© 2003 IEEE.
PY - 2003
Y1 - 2003
N2 - Under the local ischemia, the supply of sufficient oxygen and energy sources such as free fatty acid and glucose become difficult. This also affects the electrical properties of a cell membrane and it seems to be also concerned in action potential propagation velocity on the muscle fibre. In order to measure muscle function under the local ischemia, an intramuscular probe and measurement system were developed. This probe is composed of optical fiber which measures blood flow and 10 platinum fine electrodes for the action potential measurement. In gastrocnemius of rat, the action potential and blood flow were measured using this probe. The popliteal artery was ligated, and tibial nerve was electro-stimulated. With the advance of the ischemia, the potential propagation velocity, which was calculated from action potential wave got between two electrodes, gradually decreased after the ligation. In all cases of several experiments, the propagation velocity was decreased.
AB - Under the local ischemia, the supply of sufficient oxygen and energy sources such as free fatty acid and glucose become difficult. This also affects the electrical properties of a cell membrane and it seems to be also concerned in action potential propagation velocity on the muscle fibre. In order to measure muscle function under the local ischemia, an intramuscular probe and measurement system were developed. This probe is composed of optical fiber which measures blood flow and 10 platinum fine electrodes for the action potential measurement. In gastrocnemius of rat, the action potential and blood flow were measured using this probe. The popliteal artery was ligated, and tibial nerve was electro-stimulated. With the advance of the ischemia, the potential propagation velocity, which was calculated from action potential wave got between two electrodes, gradually decreased after the ligation. In all cases of several experiments, the propagation velocity was decreased.
KW - Action potential
KW - Ischemia
KW - Muscle fibre
UR - https://www.scopus.com/pages/publications/84945903913
UR - https://www.scopus.com/pages/publications/84945903913#tab=citedBy
U2 - 10.1109/APBME.2003.1302669
DO - 10.1109/APBME.2003.1302669
M3 - Conference contribution
AN - SCOPUS:84945903913
T3 - APBME 2003 - IEEE EMBS Asian-Pacific Conference on Biomedical Engineering 2003
SP - 234
EP - 235
BT - APBME 2003 - IEEE EMBS Asian-Pacific Conference on Biomedical Engineering 2003
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - IEEE EMBS Asian-Pacific Conference on Biomedical Engineering 2003, APBME 2003
Y2 - 20 October 2003 through 22 October 2003
ER -