抄録
The identification of genes specifically related to the development of metastatic disease in prostate cancer is complicated by tumor cell heterogeneity and the presence of expressed sequences that are not related to metastasis. A system was designed to minimize these complications using differential display-polymerase chain reaction (DD-PCR) together with genetically paired cell lines derived from primary mouse prostate cancer and their associated metastases generated in vivo by the metastatic mouse prostate cancer reconstitution model. Using this system, a number of metastasis-related sequences were identified, including a cDNA that encodes caveolin-1.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 422-427 |
| ページ数 | 6 |
| ジャーナル | Seminars in Oncology |
| 巻 | 26 |
| 号 | 4 |
| 出版ステータス | Published - 1999 |
| 外部発表 | はい |
ASJC Scopus subject areas
- 血液学
- 腫瘍学
