Novel quercetin glycosides as potent anti-mrsa and anti-vre agents

Abugafar M.L. Hossion, Kenji Sasaki

研究成果査読

8 被引用数 (Scopus)

抄録

Each year in the United States, at least 2 million people become infected with bacteria that are resistant to antibiotics and at least 23,000 people die each year as a direct result of these infections (Threat report 2013). Vancomycin is an FDA approved antibiotic and is growing importance in the treatment of hospital infections, with particular emphasis on its value to fight against methicillin-resistant Staphylococcus aureus (MRSA). The increasing use of vancomycin to treat infections caused by the Gram-positive MRSA in the 1970s selected for drug-resistant enterococci, less potent than staphylococci but opportunistic in the space vacated by other bacteria and in patients with compromised immune systems. The dramatic rise of antibiotic-resistant bacteria over the past two decades has stressed the need for completely novel classes of antibacterial agents. This paper reports the recent patent review on the strategy for finding novel quercetinglycoside type antibacterial agents against vancomycin-resistant bacterial strains.

本文言語English
ページ(範囲)198-205
ページ数8
ジャーナルRecent Patents on Anti-Infective Drug Discovery
8
3
DOI
出版ステータスPublished - 2013
外部発表はい

ASJC Scopus subject areas

  • 創薬
  • 感染症
  • 薬理学(医学)

フィンガープリント

「Novel quercetin glycosides as potent anti-mrsa and anti-vre agents」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル