@article{e539f71568b0440cbf861f2b2b8e06b2,
title = "Phenylhomophthalimide-type NOS inhibitors derived from thalidomide",
abstract = "Thalidomide shows moderate inhibitory activity toward neuronal nitric oxide synthase (nNOS) and inducible NOS (iNOS), but not toward endothelial NOS (eNOS). Structural development studies of thalidomide yielded novel phenylhomophthalimide-type NOS inhibitors with enhanced activity and different subtype selectivity.",
keywords = "NOS inhibitors, Structural development, Thalidomide",
author = "Tomomi Noguchi and Hiroko Sano and Rumiko Shimazawa and Aya Tanatani and Hiroyuki Miyachi and Yuichi Hashimoto",
note = "Funding Information: The work described in this paper was partially supported by Grants-in-Aid for Scientific Research from The Ministry of Education, Culture, Sports, Science, and Technology, Japan, and Japan Society for the Promotion of Science.",
year = "2004",
month = aug,
day = "16",
doi = "10.1016/j.bmcl.2004.06.026",
language = "English",
volume = "14",
pages = "4141--4145",
journal = "Bioorganic and Medicinal Chemistry Letters",
issn = "0960-894X",
publisher = "Elsevier Limited",
number = "16",
}