Plastid proteases

Zach Adam, Wataru Sakamoto

研究成果

5 被引用数 (Scopus)

抄録

Steady-state levels of chloroplast proteins rely on the balance between synthesis and degradation rates. Thus, the importance of protein-degradation processes in shaping the chloroplast proteome, and hence proper organellar functioning, cannot be overestimated. Chloroplast proteases and peptidases participate in chloroplast biogenesis through maturation or activation of pre-proteins, adaptation to changing environmental conditions through degradation of certain proteins, and maintenance of protein quality through degradation of unassembled or damaged proteins. These activities are mediated by ATP-dependent and-independent proteases, many of which are encoded by multigene families. Newly imported proteins are processed by stroma- and thylakoid-localized peptidases that remove signal sequences, which are then further degraded. The multisubunit ATP-dependent Clp and FtsH complexes degrade housekeeping and oxidatively damaged proteins in the stroma and thylakoid membranes, respectively. A number of other chloroplast proteases have been identified, but their function and substrates are still unknown, as are the nature of degradation signals and determinants of protein instability. Future research is expected to focus on these questions.

本文言語English
ホスト出版物のタイトルPlastid Biology
出版社Springer New York
ページ359-389
ページ数31
ISBN(電子版)9781493911363
ISBN(印刷版)9781493911356
DOI
出版ステータスPublished - 1月 1 2014

ASJC Scopus subject areas

  • 農業および生物科学一般

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