Resistance imparted by vitamin C, vitamin E and vitamin B₁₂ to the acute hepatic glycogen change in rats caused by noise

The effects of vitamin C, vitamin E and vitamin B₁₂ on the noise-induced acute change in hepatic glycogen content in rats were investigated. The exposure of rats to 95 dB and 110 dB of noise acutely reduced their hepatic glycogens. Vitamin C (ascorbic acid) and vitamin E (α-tocopherol) attenuated the noise-inducedacute reduction in the hepatic glycogen contents. This result suggests that antioxidants could reduce the change via reactive oxygen species. Vitamin B₁₂ (cobalamin) delayed the noise-induced change, a finding that suggests that vitamin B₁₂ could postpone the acute change via compensating for vitamin B₁₂ deficiency. Copyright