Reticalmin: A novel calcium-calmodulin-dependent protein kinase IV-like protein in rat retina

Kazuyuki Hirooka, Masaaki Tokuda, Toyohiro Tsumura, Bushra Y. Ahmed, Toshifumi Itano, Hideki Matsui, Ryoji Konishi, Eiichi Hasegawa, Sachiko Okuno, Takako Kitani, Hitoshi Fujisawa, Osamu Hatase

研究成果査読

4 被引用数 (Scopus)

抄録

Western blot analysis of 100,000g supernatant of rat retina using a polyclonal anti-Ca2+/calmodulin-dependent protein kinase IV (CaM-kinase IV) antibody revealed an immunoreactive mass of 35 kDa, termed reticalmin. Lower amount of a isoform of CaM-kinase IV was also expressed in rat retina. Reticalmin did not react with anti-CaM-kinase IV C-terminal peptide antibody which recognized α and β isoforms of CaM-kinase IV and calspermin. Immunohistochemically reticalmin was shown to be localized mainly in the outer segment of photo-receptor cells, and in dendrites of inner plexiform layers and may be in nuclei of ganglion cells and some inner nuclear layer cells.

本文言語English
ページ(範囲)2029-2033
ページ数5
ジャーナルVision Research
37
15
DOI
出版ステータスPublished - 8月 1997
外部発表はい

ASJC Scopus subject areas

  • 眼科学
  • 感覚系

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