抄録
Retinoid X receptor (RXR) antagonists are not only useful as chemical tools for biological research, but are also candidate drugs for the treatment of various diseases, including diabetes and allergies, although no RXR antagonist has yet been approved for clinical use. In this review, we present a brief overview of RXR structure, function, and target genes, and describe currently available RXR antagonists, their structural classification, and their evaluation, focusing on the latest research.
| 本文言語 | English |
|---|---|
| 論文番号 | 2354 |
| ジャーナル | International journal of molecular sciences |
| 巻 | 19 |
| 号 | 8 |
| DOI | |
| 出版ステータス | Published - 8月 10 2018 |
ASJC Scopus subject areas
- 触媒
- 分子生物学
- 分光学
- コンピュータ サイエンスの応用
- 物理化学および理論化学
- 有機化学
- 無機化学
UN SDG
この成果は、次の持続可能な開発目標に貢献しています
