Serum C3 content in vitamin B12-deficient rats

Masahiro Wada, Tetsunori Kawata, Kazuhiro Yamada, Ulala Funada, Masanori Kuwamori, Masayoshi Endo, Nobuo Tanaka, Tadahiro Tadokoro, Akio Maekawa

研究成果査読

5 被引用数 (Scopus)

抄録

As a clue to clarifying the role of vitamin B12 (B12) in the function of the complement system, serum C3 content was determined in B12-deficient rats, and the effect of the administration of methylcobalamin (CH3-B12) on the serum C3 content was also studied. It was found that the serum C3 content in rats fed on a vitamin B12-deficient diet for 90 and 120 days significantly decreased compared with that in control rats. The administration of CH3-B12 restored the serum C3 content to control levels. The above results indicate that B12-deficiency depressed the serum C3 content and lowered humoral immunocompetence, and that these changes were ascribable to B12-deficiency.

本文言語English
ページ(範囲)94-97
ページ数4
ジャーナルInternational Journal for Vitamin and Nutrition Research
68
2
出版ステータスPublished - 1998

ASJC Scopus subject areas

  • 医学(その他)
  • 内分泌学、糖尿病および代謝内科学
  • 栄養および糖尿病

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