TY - JOUR
T1 - Shift-and-add tomosynthesis of a finger joint by X-ray dark-field imaging
T2 - Difference due to tomographic angle
AU - Shimao, Daisuke
AU - Kunisada, Toshiyuki
AU - Sugiyama, Hiroshi
AU - Ando, Masami
N1 - Funding Information:
This study was approved by the High Energy Accelerator Research Organization and proceeded under proposal No. 2006G212. This study was financially supported in part by Grants-in-Aid for Young Scientists (B) (Nos. 18790900 and 18791040) and a Grant-in-Aid for Scientific Research (A) (No. 18206011) from the Ministry of Education, Culture, Sports, Science and Technology, and a Grant from The Nakajima Foundation. All funding sources had no further role in study design; in the collection, analysis and interpretation of data; in the writing of the report, or in the decision to submit the paper for publication.
PY - 2008/12
Y1 - 2008/12
N2 - A tomogram of a finger joint showing articular cartilage was generated based on X-ray dark-field imaging (XDFI) using the shift-and-add tomosynthesis algorithm. The experiment was performed at beamline 14B of the Photon Factory in Tsukuba, Japan, using synchrotron X-rays from a vertical wiggler. The incident X-ray energy was 36.0 keV. The X-ray optics for XDFI comprised two Si crystals: an asymmetric cut Si (2 2 0) monochromator-collimator and a 1.1-mm thick Si (2 2 0) Laue-case analyzer. The object was an intact cadaveric proximal interphalangeal joint fixed in formalin. Raw projection data were acquired by XDFI in a total of 41 views through an angle of 20° in 0.5° increments. The object and detector were synchronously rotated such that the fulcrum plane in the object and detector plane remained parallel. The X-ray dose for one piece of raw projection data was set to one-eleventh of that for one standard projection image by XDFI. Eleven views through an angle of 10° in increments of 1° of all 41 appropriately shifted raw projection data were added to produce arbitrary tomograms parallel to the fulcrum plane. We obtained a clear tomogram of the finger joint including the articular cartilage with the moderate artifact peculiar to tomosynthesis. Consequently, arbitrary tomograms can be obtained for the same X-ray dose as that received for one standard projection image by XDFI. The fact that an inner structure such as articular cartilage, which is invisible to conventional X-ray imaging methods, has been visualized on a tomogram with preserved refraction-enhanced contrast, is of considerable significance to clinical medicine.
AB - A tomogram of a finger joint showing articular cartilage was generated based on X-ray dark-field imaging (XDFI) using the shift-and-add tomosynthesis algorithm. The experiment was performed at beamline 14B of the Photon Factory in Tsukuba, Japan, using synchrotron X-rays from a vertical wiggler. The incident X-ray energy was 36.0 keV. The X-ray optics for XDFI comprised two Si crystals: an asymmetric cut Si (2 2 0) monochromator-collimator and a 1.1-mm thick Si (2 2 0) Laue-case analyzer. The object was an intact cadaveric proximal interphalangeal joint fixed in formalin. Raw projection data were acquired by XDFI in a total of 41 views through an angle of 20° in 0.5° increments. The object and detector were synchronously rotated such that the fulcrum plane in the object and detector plane remained parallel. The X-ray dose for one piece of raw projection data was set to one-eleventh of that for one standard projection image by XDFI. Eleven views through an angle of 10° in increments of 1° of all 41 appropriately shifted raw projection data were added to produce arbitrary tomograms parallel to the fulcrum plane. We obtained a clear tomogram of the finger joint including the articular cartilage with the moderate artifact peculiar to tomosynthesis. Consequently, arbitrary tomograms can be obtained for the same X-ray dose as that received for one standard projection image by XDFI. The fact that an inner structure such as articular cartilage, which is invisible to conventional X-ray imaging methods, has been visualized on a tomogram with preserved refraction-enhanced contrast, is of considerable significance to clinical medicine.
KW - Cartilage
KW - Laue analyzer
KW - Shift-and-add
KW - Synchrotron radiation
KW - Tomosynthesis
KW - X-ray dark field imaging
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U2 - 10.1016/j.ejrad.2008.04.037
DO - 10.1016/j.ejrad.2008.04.037
M3 - Article
C2 - 18599237
AN - SCOPUS:56549091661
SN - 0720-048X
VL - 68
SP - S27-S31
JO - European Journal of Radiology
JF - European Journal of Radiology
IS - 3 SUPPL.
ER -