Specific in vivo labeling with GFP retroviruses, lentiviruses, and adenoviruses for imaging

Robert M. Hoffman; Hiroyuki Kishimoto; Toshiyoshi Fujiwara

doi:10.1117/12.773308

Specific in vivo labeling with GFP retroviruses, lentiviruses, and adenoviruses for imaging

Robert M. Hoffman
, Hiroyuki Kishimoto
, Toshiyoshi Fujiwara

研究成果

抄録

Fluorescent proteins have revolutionized the field of imaging. Our laboratory pioneered in vivo imaging with fluorescent proteins. Fluorescent proteins have enabled imaging at the subcellular level in mice. We review here the use of different vectors carrying fluorescent proteins to selectively label normal and tumor tissue in vivo. We show that a GFP retrovirus and telomerase-driven GFP adenovirus can selectively label tumors in mice. We also show that a GFP lentivirus can selectively label the liver in mice. The practical application of these results are discussed.

本文言語	English
ホスト出版物のタイトル	Small Animal Whole-Body Optical Imaging Based on Genetically Engineered Probes
DOI	https://doi.org/10.1117/12.773308
出版ステータス	Published - 2008
イベント	Small Animal Whole-Body Optical Imaging Based on Genetically Engineered Probes - San Jose, CA 継続期間: 1月 21 2008 → 1月 22 2008

出版物シリーズ

名前	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
巻	6868
ISSN（印刷版）	1605-7422

Other

Other	Small Animal Whole-Body Optical Imaging Based on Genetically Engineered Probes
国/地域	United States
City	San Jose, CA
Period	1/21/08 → 1/22/08

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

SDG 3 すべての人に健康と福祉を

ASJC Scopus subject areas

電子材料、光学材料、および磁性材料
原子分子物理学および光学
放射線学、核医学およびイメージング
生体材料

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10.1117/12.773308

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引用スタイル

Hoffman, RM, Kishimoto, H & Fujiwara, T 2008, Specific in vivo labeling with GFP retroviruses, lentiviruses, and adenoviruses for imaging. in Small Animal Whole-Body Optical Imaging Based on Genetically Engineered Probes., 68680F, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 6868, Small Animal Whole-Body Optical Imaging Based on Genetically Engineered Probes, San Jose, CA, United States, 1/21/08. https://doi.org/10.1117/12.773308

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abstract = "Fluorescent proteins have revolutionized the field of imaging. Our laboratory pioneered in vivo imaging with fluorescent proteins. Fluorescent proteins have enabled imaging at the subcellular level in mice. We review here the use of different vectors carrying fluorescent proteins to selectively label normal and tumor tissue in vivo. We show that a GFP retrovirus and telomerase-driven GFP adenovirus can selectively label tumors in mice. We also show that a GFP lentivirus can selectively label the liver in mice. The practical application of these results are discussed.",

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AU - Fujiwara, Toshiyoshi

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N2 - Fluorescent proteins have revolutionized the field of imaging. Our laboratory pioneered in vivo imaging with fluorescent proteins. Fluorescent proteins have enabled imaging at the subcellular level in mice. We review here the use of different vectors carrying fluorescent proteins to selectively label normal and tumor tissue in vivo. We show that a GFP retrovirus and telomerase-driven GFP adenovirus can selectively label tumors in mice. We also show that a GFP lentivirus can selectively label the liver in mice. The practical application of these results are discussed.

AB - Fluorescent proteins have revolutionized the field of imaging. Our laboratory pioneered in vivo imaging with fluorescent proteins. Fluorescent proteins have enabled imaging at the subcellular level in mice. We review here the use of different vectors carrying fluorescent proteins to selectively label normal and tumor tissue in vivo. We show that a GFP retrovirus and telomerase-driven GFP adenovirus can selectively label tumors in mice. We also show that a GFP lentivirus can selectively label the liver in mice. The practical application of these results are discussed.

KW - Cancer

KW - Green fluorescent protein

KW - Liver

KW - Mouse models

KW - Selective labeling

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DO - 10.1117/12.773308

M3 - Conference contribution

AN - SCOPUS:42149149851

SN - 9780819470430

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Small Animal Whole-Body Optical Imaging Based on Genetically Engineered Probes

T2 - Small Animal Whole-Body Optical Imaging Based on Genetically Engineered Probes

Y2 - 21 January 2008 through 22 January 2008

ER -

Specific in vivo labeling with GFP retroviruses, lentiviruses, and adenoviruses for imaging

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出版物シリーズ

Other

UN SDG

ASJC Scopus subject areas

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