Syntheses and Antifungal Activities of dl-Griseofulvin and Its Congeners: I

Hideo Tomozane, Yasuo Takeuchi, Tominari Choshi, Shoko Kishida, Masatoshi Yamato

研究成果査読

23 被引用数 (Scopus)

抄録

dl-Griseofulvin (la) was prepared by two synthetic pathways. New 6'-congeners (3 and 4) of griseofulvin were also prepared. Their antifungal activities were evaluated and compounds 3 and 4 were found to be less active than la. Molecular calculations on la, dl-epigriseofulvin (lb), 3 and 4 were undertaken.

本文言語English
ページ(範囲)925-929
ページ数5
ジャーナルChemical and Pharmaceutical Bulletin
38
4
DOI
出版ステータスPublished - 1990

ASJC Scopus subject areas

  • 化学 (全般)
  • 創薬

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