Urinary excretion of aquaporin-2 in term and preterm infants

Hirokazu Tsukahara; Ikue Hata; Kyoichi Sekine; Masakazu Miura; Keishi Hata; Yasushi Fujii; Mitsufumi Mayumi

doi:10.1016/S0378-3782(97)00072-8

Urinary excretion of aquaporin-2 in term and preterm infants

Hirokazu Tsukahara, Ikue Hata, Kyoichi Sekine, Masakazu Miura, Keishi Hata, Yasushi Fujii, Mitsufumi Mayumi

研究成果 › 査読

4 被引用数 (Scopus)

抄録

Aquaporin-2 (AQP-2) is a vasopressin-regulated water channel of the renal collecting duct and is excreted in human urine. We measured the urinary excretion of AQP-2 by radioimmunoassay in 14 term and 12 preterm infants aged 1 month. Excretion of AQP-2 was low compared with adults, and correlated significantly with urine osmolality in preterm infants. Our results demonstrate that AQP-2 water channels are expressed in the renal collecting duct of both term and preterm infants.

本文言語	English
ページ（範囲）	31-37
ページ数	7
ジャーナル	Early Human Development
巻	51
号	1
DOI	https://doi.org/10.1016/S0378-3782(97)00072-8
出版ステータス	Published - 4月 17 1998
外部発表	はい

ASJC Scopus subject areas

小児科学、周産期医学および子どもの健康
産婦人科学

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10.1016/S0378-3782(97)00072-8

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abstract = "Aquaporin-2 (AQP-2) is a vasopressin-regulated water channel of the renal collecting duct and is excreted in human urine. We measured the urinary excretion of AQP-2 by radioimmunoassay in 14 term and 12 preterm infants aged 1 month. Excretion of AQP-2 was low compared with adults, and correlated significantly with urine osmolality in preterm infants. Our results demonstrate that AQP-2 water channels are expressed in the renal collecting duct of both term and preterm infants.",

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AU - Tsukahara, Hirokazu

AU - Hata, Ikue

AU - Sekine, Kyoichi

AU - Miura, Masakazu

AU - Hata, Keishi

AU - Fujii, Yasushi

AU - Mayumi, Mitsufumi

PY - 1998/4/17

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N2 - Aquaporin-2 (AQP-2) is a vasopressin-regulated water channel of the renal collecting duct and is excreted in human urine. We measured the urinary excretion of AQP-2 by radioimmunoassay in 14 term and 12 preterm infants aged 1 month. Excretion of AQP-2 was low compared with adults, and correlated significantly with urine osmolality in preterm infants. Our results demonstrate that AQP-2 water channels are expressed in the renal collecting duct of both term and preterm infants.

AB - Aquaporin-2 (AQP-2) is a vasopressin-regulated water channel of the renal collecting duct and is excreted in human urine. We measured the urinary excretion of AQP-2 by radioimmunoassay in 14 term and 12 preterm infants aged 1 month. Excretion of AQP-2 was low compared with adults, and correlated significantly with urine osmolality in preterm infants. Our results demonstrate that AQP-2 water channels are expressed in the renal collecting duct of both term and preterm infants.

KW - Aquaporin-2

KW - Infants

KW - Urine

KW - Vasopressin

KW - Water balance

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Urinary excretion of aquaporin-2 in term and preterm infants

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