Zamamiphidin A, a new manzamine related alkaloid from an Okinawan marine sponge amphimedon sp.

Takaaki Kubota; Yuki Kamijyo; Azusa Takahashi-Nakaguchi; Jane Fromont; Tohru Gonoi; Jun'Ichi Kobayashi

doi:10.1021/ol3034274

Zamamiphidin A, a new manzamine related alkaloid from an Okinawan marine sponge amphimedon sp.

Takaaki Kubota, Yuki Kamijyo, Azusa Takahashi-Nakaguchi, Jane Fromont, Tohru Gonoi, Jun'Ichi Kobayashi

研究成果 › 査読

20 被引用数 (Scopus)

抄録

A manzamine related alkaloid, zamamiphidin A (1), consisting of a new heptacyclic ring system has been isolated from an Okinawan marine sponge Amphimedon sp. The structure of 1 including the relative stereochemistry was elucidated on the basis of the spectroscopic data. Compound 1 showed antibacterial activity against Staphylococcus aureus (MIC, 32 μg/mL).

本文言語	English
ページ（範囲）	610-612
ページ数	3
ジャーナル	Organic Letters
巻	15
号	3
DOI	https://doi.org/10.1021/ol3034274
出版ステータス	Published - 2月 1 2013
外部発表	はい

ASJC Scopus subject areas

生化学
物理化学および理論化学
有機化学

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

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10.1021/ol3034274

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AU - Kubota, Takaaki

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AU - Takahashi-Nakaguchi, Azusa

AU - Fromont, Jane

AU - Gonoi, Tohru

AU - Kobayashi, Jun'Ichi

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N2 - A manzamine related alkaloid, zamamiphidin A (1), consisting of a new heptacyclic ring system has been isolated from an Okinawan marine sponge Amphimedon sp. The structure of 1 including the relative stereochemistry was elucidated on the basis of the spectroscopic data. Compound 1 showed antibacterial activity against Staphylococcus aureus (MIC, 32 μg/mL).

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Zamamiphidin A, a new manzamine related alkaloid from an Okinawan marine sponge amphimedon sp.

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ASJC Scopus subject areas

UN SDG

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